Skip to main content
Book A Free Consult

Home » What's New » Re: Mitomycin-C OTA — published in June Ophthalmology

Re: Mitomycin-C OTA — published in June Ophthalmology


Dear All,

I would highly recommend the above EXCELLENT review article (link below). Many of our colleagues worked very hard to produce and excellent summary of the “state of the art”.


Highland Park, IL


dear randy, parag, roy, and everyone else

i just read this article in the blue journal, it agree it was very good and long overdue

it did say “we are not sure what the minimum effective dose in terms of concentration and time is” or something like that

i did a poster w my MD PhD fellow last year

where we compared 0.01% MMC for 10 sec in 1 eye vs proportional to Rx/ablation time in the other eye

and found the shorter time to be equally effective in preventing scarring, ie no dose-response curve

maybe bc, as others have found, the effect of MMC is so rapid/strong you get a full effect at a very low %/time

we submitted this for publication, i think to AJO or JCRS or something like that, but got rejected

we are planning on resubmitting to an easier journal, bc our study is clearly not exactly groundbreaking

but it would help answer the question of “how low can you go” as we were at 1/2 the concentration of the common %

and at the lowest time commonly reported

can i have some suggestions on which lesser journal to submit to, as i do think it’s worth publishing

and i don’t want to go through the pain of submitting and getting rejected from a top 5 journal

so something ranked 6-10 in ophtho for impact factor would probably be more appropriate

thanks in advance for your kind help; pls reply to all (maybe taking off the knet group)

as my 2 co-authors dr b and an intern in DO school are ccd



*Emil William Chynn, MD, FACS, MBA*

No other laser vision correction surgeon in New York….

No other laser vision correction surgeon in New York....

...offers you the opportunity to have a Free Remote Consultation with the surgeon! Ask Dr. Chynn your main question or concern, and will answer, personally, within 2 business days!

Unsure whether you're a good candidate because of a lot of astigmatism? Large pupils? Dry eyes? Maybe you were rejected by LASIK surgeons due to a “thin cornea” or high prescription.

Take advantage of this incredible opportunity to find out if LASEK is an option for you from Dr. Chynn, our famous, cornea fellowship-trained, Columbia & Harvard graduate who’s in MENSA & was the 1st eye surgeon in NY, NJ, CT & PA to get LASIK, & has performed 1,000 PRKs, 5,000 LASIKs, 10,000 LASEKs, and 5,000 epiLASEKs

But please be considerate. Dr. Chynn gets paid $1,000/hour as a consultant for expert networks & expert witness, so please limit yourself to your most pressing question or concern, as he’s doing this for free on a trial basis to help interested patients.

Please include the information below in your email so Dr. Chynn can answer your question specifically.

Approximate prescription (if known):
Occupation (the more specific the better):
Main barrier or concern:

  • This field is for validation purposes and should be left unchanged.

Ask Dr. Chynn

interstitial v1